O-Chem for MCAT

Do you already know these?:

• Benzene ring is super stable.
• Ortho, meta, and para positions.

Since you already know that benzene is a hard bitch to break, let’s talk about how substituents can affect it:

I.  Activators & Weak Deactivators are OP-directors

II. Strong Deactivators are M-directors

<more to come>