Optimising the IP-RP analysis of protected and unprotected oligonucleotides
Short oligonucleotides are usually produced via solid phase synthesis. To achieve a controlled sequence the 5’ terminus is protected with a protecting group such as dimethoxytrityl (DMT). After the successful synthesis, specifically after every synthetic step, the protecting group is removed....
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Chromatography Today - Buyers' Guide 2022
October 2023
In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
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